Chemical Properties:
Package: Bottle, 25kg/Barrel or 200kg/Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.Manufacturer Supply With High Quality, Commercial Production Chemical Name: Diethyl Cyanomethylphosphonate CAS: 2537-48-6| Item | Specifications |
| Appearance | Colorless Transparent Liquid |
| Purity / Analysis Method | >99.0% (GC) |
| Moisture (K.F) | <0.50% |
| Acid Value (mgKOH/g) | <2.00 |
| Total Impurities | <1.00% |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediates; Horner-Emmons Reagents |
Description:
Specifications:
Package & Storage:
| Chemical Name | Diethyl Cyanomethylphosphonate |
| Synonyms | Cyanomethylphosphonic Acid Diethyl Ester |
| CAS Number | 2537-48-6 |
| CAT Number | RF-PI1252 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C6H12NO3P |
| Molecular Weight | 177.14 |
| Boiling Point | 101.0~102.0℃/0.4 mm Hg(lit.) |
| Density | 1.095 g/ml at 25℃ (lit.) |
| Refractive Index | N20/D 1.431~1.435 |
| Brand | Ruifu Chemical |
Advantages:
FAQ:
Application:
Diethyl Cyanomethylphosphonate (CAS: 2537-48-6) is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.
